Evidence that the thyrotropin-releasing hormone receptor and its ligand are recycled dissociated from each other.

We have examined the trafficking of the thyrotropin-releasing hormone receptor (TRHR) and its ligand, after TRHR-TRH internalization in rat pituitary GH4C1 cells. After rapid ligand-induced receptor sequestration, the cell surface receptor pool was replenished. Replenishment was insensitive to inhib...

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Autors principals: Petrou, C P, Tashjian, A H
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136488/
https://ncbi.nlm.nih.gov/pubmed/7864795
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