Lysosomal processing of amyloid precursor protein to A beta peptides: a distinct role for cathepsin S.

To investigate the potential contribution of the lysosomal compartment in the processing of amyloid precursor protein (APP) to amyloid beta-peptides (A beta s), we stably overexpressed a series of lysosomal proteases (the cysteine proteases, cathepsins B, L and S, and the aspartic protease, cathepsi...

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Detalhes bibliográficos
Main Authors: Munger, J S, Haass, C, Lemere, C A, Shi, G P, Wong, W S, Teplow, D B, Selkoe, D J, Chapman, H A
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136152/
https://ncbi.nlm.nih.gov/pubmed/7575468
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