Na+/H+ exchange modulates the production of leukotriene B4 by human neutrophils.

Human neutrophils produce various compounds of the 5-lipoxygenase pathway, including (5S)-hydroxyeicosatetraenoic acid, leukotriene B4, its 6-trans isomers and omega-oxidation metabolites of LTB4, when the cells are stimulated with the Ca2+ ionophore A23187. The elevation in the extracellular pH (pH...

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Bibliografiske detaljer
Main Authors: Osaki, M, Sumimoto, H, Takeshige, K, Cragoe, E J, Hori, Y, Minakami, S
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135652/
https://ncbi.nlm.nih.gov/pubmed/2539095
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