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Evidence that a novel serine kinase catalyses phosphorylation of the insulin receptor in an insulin-dependent and tyrosine kinase-dependent manner.

Insulin receptor was co-purified from human placenta together with insulin-stimulated kinase activity that phosphorylates the insulin receptor on serine residues. By using this 'in vitro' system, the mechanism of activation of the serine kinase by insulin was explored. Peptide 1150, histon...

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Detalles Bibliográficos
Main Authors: Smith, D M, Sale, G J
Formato: Artigo
Idioma:Inglês
Publicado: 1988
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135501/
https://ncbi.nlm.nih.gov/pubmed/2975946
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