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Role of compartmentalized redox-active iron in hydrogen peroxide-induced DNA damage and apoptosis
Jurkat cells in culture were exposed to oxidative stress in the form of continuously generated hydrogen peroxide, obtained by the addition of glucose oxidase to the medium. This treatment induced a rapid, dose-dependent increase in the ICIP (intracellular calcein-chelatable iron pool). Early destabi...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Portland Press Ltd.
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1135000/ https://ncbi.nlm.nih.gov/pubmed/15579135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041650 |
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