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Critical role for Ets, AP-1 and GATA-like transcription factors in regulating mouse Toll-like receptor 4 (Tlr4) gene expression

TLR4 (Toll-like receptor 4) is essential for sensing the endotoxin of Gram-negative bacteria. Mutations or deletion of the TLR4 gene in humans or mice have been associated with altered predisposition to or outcome of Gram-negative sepsis. In the present work, we studied the expression and regulation...

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Detalhes bibliográficos
Main Authors: Roger, Thierry, Miconnet, Isabelle, Schiesser, Anne-Laure, Kai, Hirofumi, Miyake, Kensuke, Calandra, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134963/
https://ncbi.nlm.nih.gov/pubmed/15537384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041243
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