Direct activation of human neutrophil procollagenase by recombinant stromelysin.

Human neutrophil procollagenase was activated by incubation with recombinant active stromelysin. Activation was achieved by cleavage of the Gly78-Phe79 peptide bond at the end of the propeptide domain in a single-step activation mechanism. In addition, accelerated activation was achieved when N-term...

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Autors principals: Knäuper, V, Wilhelm, S M, Seperack, P K, DeClerck, Y A, Langley, K E, Osthues, A, Tschesche, H
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134920/
https://ncbi.nlm.nih.gov/pubmed/8240261
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