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A mitochondrial pool of sphingomyelin is involved in TNFα-induced Bax translocation to mitochondria
We recently showed that targeting bSMase (bacterial sphingomyelinase) specifically to mitochondria caused accumulation of ceramide in mitochondria, and induced cytochrome c release and cell death [Birbes, El Bawab, Hannun and Obeid (2001) FASEB J., 15, 2669–2679]. In the present study, we investigat...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1134862/ https://ncbi.nlm.nih.gov/pubmed/15516208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041627 |
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