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Isoprenoid biosynthesis as a target for antibacterial and antiparasitic drugs: phosphonohydroxamic acids as inhibitors of deoxyxylulose phosphate reducto-isomerase

Isoprenoid biosynthesis via the methylerythritol phosphate pathway is a target against pathogenic bacteria and the malaria parasite Plasmodium falciparum. 4-(Hydroxyamino)-4-oxobutylphosphonic acid and 4-[hydroxy(methyl)amino]-4-oxobutyl phosphonic acid, two novel inhibitors of DXR (1-deoxy-D-xylulo...

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Detaylı Bibliyografya
Asıl Yazarlar: Kuntz, Lionel, Tritsch, Denis, Grosdemange-Billiard, Catherine, Hemmerlin, Andréa, Willem, Audrey, Bach, Thomas J., Rohmer, Michel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Portland Press Ltd. 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134774/
https://ncbi.nlm.nih.gov/pubmed/15473867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041378
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