Inhibition of Rac activation as a mechanism for negative regulation of actin cytoskeletal reorganization and cell motility by cAMP

cAMP has been found to play a role in mediating the negative regulation of cell motility, although its underlying molecular mechanism remains poorly understood. By using CHO (Chinese-hamster ovary) cells that express the EP2 subtype of PGE(2) (prostaglandin E(2)) receptors, we provide evidence that...

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Hlavní autoři: Nagasawa, Shin-ya, Takuwa, Noriko, Sugimoto, Naotoshi, Mabuchi, Hiroshi, Takuwa, Yoh
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2005
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134749/
https://ncbi.nlm.nih.gov/pubmed/15377280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041060
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