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Reaction of artemisinin with haemoglobin: implications for antimalarial activity

Elucidation of the principal targets of the action of the antimalarial drug artemisinin is an ongoing pursuit that is important for understanding the action of this drug and for the development of more potent analogues. We have examined the chemical reaction of Hb with artemisinin. The protein-bound...

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Detalhes bibliográficos
Main Authors: Kannan, Rangiah, Kumar, Krishan, Sahal, Dinkar, Kukreti, Shrikant, Chauhan, Virander S.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134711/
https://ncbi.nlm.nih.gov/pubmed/15361062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041170
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