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Activation of an α(2A)-adrenoceptor–Gα(o1) fusion protein dynamically regulates the palmitoylation status of the G protein but not of the receptor
Post-translational thio-acylation of a fusion protein between the α(2A)-adrenoceptor and the α subunit of the G protein G(o1) is both dynamic and regulated by agonist binding. Incorporation of [(3)H]palmitate into the fusion protein was reduced substantially in the presence of the agonist adrenaline...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1134688/ https://ncbi.nlm.nih.gov/pubmed/15362975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041432 |
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