The palmitoylation status of the G-protein G(o)1 alpha regulates its activity of interaction with the plasma membrane.

Plasmids containing cDNAs encoding either the wild-type guanine-nucleotide-binding protein G(o)1 alpha or the palmitoylation-negative cysteine-3-to-serine (C3S) mutant of G(o)1 alpha were transfected into Rat 1 cells, and clones stably expressing immunoreactivity corresponding to these polypeptides...

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Bibliographic Details
Main Authors: Grassie, M A, McCallum, J F, Guzzi, F, Magee, A I, Milligan, G, Parenti, M
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137317/
https://ncbi.nlm.nih.gov/pubmed/7945220
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