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The BIR domain of IAP-like protein 2 is conformationally unstable: implications for caspase inhibition

Several IAP (inhibitor of apoptosis) proteins regulate cell fate decisions, and the X-linked IAP (XIAP) does so in part by inhibiting caspases, proteases that execute the apoptotic pathway. A tissue-specific homologue of XIAP, known as ILP2 (IAP-like protein 2), has previously been implicated in the...

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Main Authors: Shin, Hwain, Renatus, Martin, Eckelman, Brendan P., Nunes, Viviane A., Sampaio, Claudio A. M., Salvesen, Guy S.
格式: Artigo
語言:Inglês
出版: Portland Press Ltd. 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134667/
https://ncbi.nlm.nih.gov/pubmed/15485395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041107
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