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Substrate-induced inactivation of the OXA2 beta-lactamase.

The hydrolysis time courses of 22 beta-lactam antibiotics by the class D OXA2 beta-lactamase were studied. Among these, only three appeared to correspond to the integrated Henri-Michaelis equation. 'Burst' kinetics, implying branched pathways, were observed with most penicillins, cephalosp...

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Detalhes bibliográficos
Main Authors: Ledent, P, Frère, J M
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134642/
https://ncbi.nlm.nih.gov/pubmed/8240304
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