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Interleukin-1 activates transcription factor NF kappa B in glial cells.

Recombinant human interleukin-1 (IL-1) alpha and beta were found to activate a latent cytosolic form of the transcription factor NF kappa B in rat C6 glioma. IL-1 beta was 10 times more potent than IL-1 alpha for this activity and both were inhibited by the IL-1 receptor antagonist. The activation w...

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Autors principals: Moynagh, P N, Williams, D C, O'Neill, L A
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134460/
https://ncbi.nlm.nih.gov/pubmed/8373349
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