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A misassembled transmembrane domain of a polytopic protein associates with signal peptide peptidase

The endoplasmic reticulum (ER) exerts a quality control over newly synthesized proteins and a variety of components have been implicated in the specific recognition of aberrant or misfolded polypeptides. We have exploited a site-specific cross-linking approach to search for novel ER components that...

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Библиографические подробности
Главные авторы: Crawshaw, Samuel G., Martoglio, Bruno, Meacock, Suzanna L., High, Stephen
Формат: Artigo
Язык:Inglês
Опубликовано: Portland Press Ltd. 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134083/
https://ncbi.nlm.nih.gov/pubmed/15373738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041216
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