Slow-binding inhibitors of prolyl oligopeptidase with different functional groups at the P1 site

POP (prolyl oligopeptidase) specifically hydrolyses a number of small proline-containing peptides at the carboxy end of the proline residue and POP inhibitors have been shown to have cognition-enhancing properties. It has been noted that certain functional groups at the P1 site of the inhibitor, whi...

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Detalhes bibliográficos
Main Authors: VENäLäINEN, Jarkko I., Juvonen, Risto O., Garcia-Horsman, J. Arturo, WALLéN, Erik A. A., Christiaans, Johannes A. M., Jarho, Elina M., Gynther, Jukka, MäNNISTö, Pekka T.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133977/
https://ncbi.nlm.nih.gov/pubmed/15217351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040992
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