Mature bovine articular cartilage contains abundant aggrecan that is C-terminally truncated at Ala(719)-Ala(720), a site which is readily cleaved by m-calpain

Extracts of normal mature articular cartilage contain aggrecan molecules which bear the G1 domain (the N-terminal globular domain of aggrecan) and are C-terminally truncated by proteolysis at a number of sites. A proportion of these molecules are generated by an aggrecanase and/or matrix-metalloprot...

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Bibliographische Detailangaben
Hauptverfasser: Oshita, Hidefumi, Sandy, John D., Suzuki, Kiichi, Akaike, Atsushi, Bai, Yun, Sasaki, Tomohiro, Shimizu, Katsuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2004
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133938/
https://ncbi.nlm.nih.gov/pubmed/15175011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040113
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