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Conformational changes in gastric H(+)/K(+)-ATPase monitored by difference Fourier-transform infrared spectroscopy and hydrogen/deuterium exchange
Gastric H(+)/K(+)-ATPase is a P-type ATPase responsible for acid secretion in the stomach. This protein adopts mainly two conformations called E1 and E2. Even though two high-resolution structures for a P-ATPase in these conformations are available, little structural information is available about t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1133922/ https://ncbi.nlm.nih.gov/pubmed/15096097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040277 |
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