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Characterization of bromosulphophthalein binding to human glutathione S-transferase A1-1: thermodynamics and inhibition kinetics

In addition to their catalytic functions, GSTs (glutathione S-transferases) bind a wide variety of structurally diverse non-substrate ligands. This ligandin function is known to result in the inhibition of catalytic function. The interaction between hGSTA1-1 (human class Alpha GST with two type 1 su...

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Autors principals: Kolobe, Doris, Sayed, Yasien, Dirr, Heini W.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133828/
https://ncbi.nlm.nih.gov/pubmed/15147239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040056
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