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Phospholipase D activation is functionally linked to superoxide generation in the human neutrophil.

Neutrophils stimulated with formylmethionyl-leucylphenylalanine (fMet-Leu-Phe) in the presence of butanol and ethanol formed phosphatidyl alcohols through a phospholipase D mechanism. The alcohols inhibited phosphatidic acid and diradylglycerol (DRG) formation, but did not block inositol 1, 4, 5-tri...

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Detalhes bibliográficos
Main Authors: Bonser, R W, Thompson, N T, Randall, R W, Garland, L G
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133625/
https://ncbi.nlm.nih.gov/pubmed/2557846
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