Tyrosine phosphorylation is involved in receptor coupling to phospholipase D but not phospholipase C in the human neutrophil.

The tyrosine kinase inhibitors ST271, ST638 and erbstatin inhibited phospholipase D (PLD) activity in human neutrophils stimulated by fMet-Leu-Phe, platelet-activating factor and leukotriene B4. These compounds did not inhibit phorbol ester-stimulated PLD, indicating that they do not inhibit PLD per...

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Détails bibliographiques
Auteurs principaux: Uings, I J, Thompson, N T, Randall, R W, Spacey, G D, Bonser, R W, Hudson, A T, Garland, L G
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1130730/
https://ncbi.nlm.nih.gov/pubmed/1371383
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