Defective activity of acyl-CoA:cholesterol O-acyltransferase in Niemann-Pick type C and type D fibroblasts.

The activity of acyl-CoA:cholesterol acyltransferase (ACAT; EC 2.3.1.26) was measured in fibroblast homogenates from Niemann-Pick Type C (NPC) and Type D (NPD) patients to determine whether these cells exhibit similar defects in the regulation of cholesterol esterification. ACAT activity in normal c...

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Dettagli Bibliografici
Autori principali: Byers, D M, Rastogi, S R, Cook, H W, Palmer, F B, Spence, M W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1989
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133333/
https://ncbi.nlm.nih.gov/pubmed/2590161
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