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Evaluation of hydrogen-bonding and enantiomeric P2-S2 hydrophobic contacts in dynamic aspects of molecular recognition by papain.

1. 2-(N'-Acetyl-D-phenylalanyl)hydroxyethyl 2'-pyridyl disulphide (compound IV) (m.p. 59 degrees C; [alpha]D20 -6.6 degrees (c 1.2 in methanol)) was synthesized. 2. The results of a study of the pH-dependence of the second-order rate constant (k) for its reaction with the catalytic-site th...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Patel, M, Kayani, I S, Templeton, W, Mellor, G W, Thomas, E W, Brocklehurst, K
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1992
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133089/
https://ncbi.nlm.nih.gov/pubmed/1445247
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