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Activation of protein kinase C is not an absolute requirement for amylase release from permeabilized rat pancreatic acini.

The effect of protein kinase C (PKC) on amylase discharge from streptolysin-O-permeabilized rat pancreatic acini was investigated. Addition of phorbol 12-myristate 13-acetate (PMA) to permeabilized cells potentiated Ca(2+)-stimulated release, but had no effect on discharge at non-stimulatory Ca2+ co...

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Autors principals: O'Sullivan, A J, Jamieson, J D
Format: Artigo
Idioma:Inglês
Publicat: 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132830/
https://ncbi.nlm.nih.gov/pubmed/1379047
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