Canarypox Virus-Induced Maturation of Dendritic Cells Is Mediated by Apoptotic Cell Death and Tumor Necrosis Factor Alpha Secretion

Recombinant avipox viruses are being widely evaluated as vaccines. To address how these viruses, which replicate poorly in mammalian cells, might be immunogenic, we studied how canarypox virus (ALVAC) interacts with primate antigen-presenting dendritic cells (DCs). When human and rhesus macaque mono...

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Detalhes bibliográficos
Main Authors: Ignatius, Ralf, Marovich, Mary, Mehlhop, Erin, Villamide, Loreley, Mahnke, Karsten, Cox, William I., Isdell, Frank, Frankel, Sarah S., Mascola, John R., Steinman, Ralph M., Pope, Melissa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113238/
https://ncbi.nlm.nih.gov/pubmed/11070033
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