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Expression, purification and characterization of B72.3 Fv fragments.

The Fv fragment of the antibody B72.3 has been produced by expression in both a mammalian and microbial system, namely Chinese hamster ovary (CHO) cells and Escherichia coli. In both cases secretion of the Fv into the culture medium was achieved, with equivalent amounts of Vh and Vl produced. The yi...

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Autores principales: King, D J, Byron, O D, Mountain, A, Weir, N, Harvey, A, Lawson, A D, Proudfoot, K A, Baldock, D, Harding, S E, Yarranton, G T
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132340/
https://ncbi.nlm.nih.gov/pubmed/8457200
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