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Generating segmental mutations in haloalkane dehalogenase: a novel part in the directed evolution toolbox

Directed evolution techniques allow us to genuinely mimic molecular evolution in vitro. To enhance this imitation of natural evolutionary processes on a laboratory scale in even more detail, we developed an in vitro method for the generation of random deletions and repeats. The pairwise fusion of tw...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Pikkemaat, Mariël G., Janssen, Dick B.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113230/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11937643/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.8.e35
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