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Affinity labelling of the Ca(2+)-activated neutral proteinase (calpain) in intact human platelets.

Two irreversible calpain inhibitors, benzyloxycarbonyl (Cbz)-Leu-Leu-Tyr-Ch2F and Cbz-Leu-Leu-Tyr-CHN2, were shown earlier [Anagli, Hagmann and Shaw (1991) Biochem. J. 274, 497-502] to penetrate intact platelets and to inactivate calpain. This permitted an evaluation of certain functions attributed...

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Bibliografiske detaljer
Main Authors: Anagli, J, Hagmann, J, Shaw, E
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132135/
https://ncbi.nlm.nih.gov/pubmed/8424777
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