Evidence of H- and L-chains have co-operative roles in the iron-uptake mechanism of human ferritin.

The ability to incorporate iron in vitro was studied in homopolymers of human ferritin L-chain, human ferritin H-chain and its variants and in homopolymer mixtures. The H-chain variants carried amino acid substitutions in the ferroxidase centre and/or in carboxy residues on the cavity surface. Iron...

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Bibliographic Details
Main Authors: Levi, S, Yewdall, S J, Harrison, P M, Santambrogio, P, Cozzi, A, Rovida, E, Albertini, A, Arosio, P
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132051/
https://ncbi.nlm.nih.gov/pubmed/1463463
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