Dual effect of fluoride on phosphoinositide metabolism in rat brain cortex. Stimulation of phospholipase C and inhibition of polyphosphoinositide synthesis.

We have studied the effects of fluoride, guanosine 5'-[gamma-thio]triphosphate (GTP[S]) and carbachol on phospholipase C and polyphosphoinositide synthesis. The experimental system consisted of membranes from rat brain cortex, with exogenous [3H]phosphatidylinositol ([3H]PtdIns) as substrate. I...

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Bibliografski detalji
Glavni autori: Claro, E, Wallace, M A, Fain, J N
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131501/
https://ncbi.nlm.nih.gov/pubmed/2163621
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