The DNA strand of chimeric RNA/DNA oligonucleotides can direct gene repair/conversion activity in mammalian and plant cell-free extracts

Chimeric oligonucleotides (chimeras), consisting of RNA and DNA bases folded by complementarity into a double hairpin conformation, have been shown to alter or repair single bases in plant and animal genomes. An uninterrupted stretch of DNA bases within the chimera is known to be active in the seque...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Gamper, Howard B., Parekh, Hetal, Rice, Michael C., Bruner, Michael, Youkey, Heather, Kmiec, Eric B.
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2000
Matèries:	Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113138/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11058133/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.21.4332
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