Concanavalin A-induced receptor aggregation stimulates the tyrosine kinase activity of the insulin receptor in intact cells.

Concanavalin A (ConA) stimulated the phosphorylation of the beta-subunit of the insulin receptor and an Mr-185,000 protein on serine and tyrosine residues in intact H-35 rat hepatoma cells. This Mr-185,000 protein whose phosphorylation was stimulated by ConA was identical to pp185, a protein reporte...

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Detalhes bibliográficos
Main Authors: Shiba, T, Tobe, K, Koshio, O, Yamamoto, R, Shibasaki, Y, Matsumoto, N, Toyoshima, S, Osawa, T, Akanuma, Y, Takaku, F
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131367/
https://ncbi.nlm.nih.gov/pubmed/2339989
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