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The tyrosine kinase activity of the epidermal-growth-factor receptor is necessary for phospholipase A2 activation.

We have previously reported that epidermal growth factor (EGF) activates phospholipase A2 (PLA2) independently of phospholipase C (PLC) in renal mesangial cells. In this study we use NIH 3T3 cell lines transfected with the normal EGF receptor (HER14 cells) or with EGF receptor defective in tyrosine...

詳細記述

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書誌詳細
主要な著者: Goldberg, H J, Viegas, M M, Margolis, B L, Schlessinger, J, Skorecki, K L
フォーマット: Artigo
言語:Inglês
出版事項: 1990
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131311/
https://ncbi.nlm.nih.gov/pubmed/2159283
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