The tyrosine kinase activity of the epidermal-growth-factor receptor is necessary for phospholipase A2 activation.

We have previously reported that epidermal growth factor (EGF) activates phospholipase A2 (PLA2) independently of phospholipase C (PLC) in renal mesangial cells. In this study we use NIH 3T3 cell lines transfected with the normal EGF receptor (HER14 cells) or with EGF receptor defective in tyrosine...

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Detalhes bibliográficos
Main Authors: Goldberg, H J, Viegas, M M, Margolis, B L, Schlessinger, J, Skorecki, K L
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131311/
https://ncbi.nlm.nih.gov/pubmed/2159283
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