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Signal transduction by the epidermal growth factor receptor after functional desensitization of the receptor tyrosine protein kinase activity.

Previous work identified a protein kinase activity that phosphorylates the epidermal growth factor (EGF) receptor at Thr669. An assay for this protein kinase activity present in homogenates prepared from A431 human epidermoid carcinoma cells was developed using a synthetic peptide substrate correspo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Northwood, I C, Davis, R J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54481/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2166944/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.16.6107
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