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Photoaffinity labelling of isopenicillin N synthetase.

The alpha-aminoadipoyl group of the natural substrate of isopenicillin N synthetase (IPNS), L-alpha-aminoadipoyl-L-cysteinyl-D-valine (ACV), has been replaced by a diazirinyl-containing group, which can be photoactivated. This has allowed investigation of the substrate binding site of IPNS by photoa...

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Bibliografische gegevens
Hoofdauteurs: Baldwin, J E, Coates, J B, Moloney, M G, Pratt, A J, Willis, A C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1990
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131168/
https://ncbi.nlm.nih.gov/pubmed/2317203
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