Synthesis of tritium-labelled isopenicillin N, penicillin N and 6-aminopenicillanic acid.

1. Phenoxymethylpenicillin sulphoxide 4-methoxybenzyl ester was labelled with 3H in its 2-beta-methyl group. Its specific radioactivity was 362 mCi/mmol. 2. Removal of the side chain of this compound yielded the corresponding ester of 6-aminopenicillanic acid sulphoxide and coupling of the latter wi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Usher, J J, Loder, B, Abraham, E P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1975
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1172422/
https://ncbi.nlm.nih.gov/pubmed/175787
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