The URNA Genes of Herpesvirus Saimiri (Strain C488) Are Dispensable for Transformation of Human T Cells In Vitro

The herpesvirus saimiri strain C488 genome contains five genes for small nuclear RNAs, termed herpesvirus saimiri URNAs (or HSURs). Using a cosmid-based approach, all HSURs were precisely deleted from the genome. The mutant virus replicated at levels that were similar to those of wild-type viruses i...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Ensser, Armin, Pfinder, André, Müller-Fleckenstein, Ingrid, Fleckenstein, Bernhard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Transformation and Oncogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113114/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10559377/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.12.10551-10555.1999
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