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The URNA Genes of Herpesvirus Saimiri (Strain C488) Are Dispensable for Transformation of Human T Cells In Vitro

The herpesvirus saimiri strain C488 genome contains five genes for small nuclear RNAs, termed herpesvirus saimiri URNAs (or HSURs). Using a cosmid-based approach, all HSURs were precisely deleted from the genome. The mutant virus replicated at levels that were similar to those of wild-type viruses i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ensser, Armin, Pfinder, André, Müller-Fleckenstein, Ingrid, Fleckenstein, Bernhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC113114/
https://ncbi.nlm.nih.gov/pubmed/10559377
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