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Dependence of Echovirus 9 on the Enterovirus RNA Replication Inhibitor 2-(α-Hydroxybenzyl)-Benzimidazole Maps to Nonstructural Protein 2C

HBB [2-(α-hydroxybenzyl)-benzimidazole] selectively inhibits RNA synthesis of most enteroviruses. However, isolation of HBB-dependent variants is possible. Sequence analysis and characterization of recombinant viruses revealed that HBB dependence maps to the nonstructural protein 2C. A single point...

詳細記述

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書誌詳細
主要な著者: Hadaschik, Dirk, Klein, Marcus, Zimmermann, Holger, Eggers, Hans J., Nelsen-Salz, Birgit
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC113111/
https://ncbi.nlm.nih.gov/pubmed/10559374
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