Inhibition of bacterial protein synthesis by elongation-factor-Tu-binding antibiotics MDL 62,879 and efrotomycin.

MDL 62,879 (formerly GE 2270 A) is a novel antibiotic active against Gram-positive bacteria by inhibiting protein synthesis. MDL 62,879 is not active against Gram-negative bacteria, but inhibits cell-free protein synthesis in extracts from Escherichia coli, and shows a high binding affinity for its...

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Hlavní autoři: Landini, P, Bandera, M, Goldstein, B P, Ripamonti, F, Soffientini, A, Islam, K, Denaro, M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1130934/
https://ncbi.nlm.nih.gov/pubmed/1590753
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