Efficient Processing of the Immunodominant, HLA-A*0201-Restricted Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitope despite Multiple Variations in the Epitope Flanking Sequences

Immune escape from cytotoxic T-lymphocyte (CTL) responses has been shown to occur not only by changes within the targeted epitope but also by changes in the flanking sequences which interfere with the processing of the immunogenic peptide. However, the frequency of such an escape mechanism has not b...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Brander, Christian, Yang, Otto O., Jones, Norman G., Lee, Yun, Goulder, Philip, Johnson, R. Paul, Trocha, Alicja, Colbert, David, Hay, Christine, Buchbinder, Susan, Bergmann, Cornelia C., Zweerink, Hans J., Wolinsky, Steven, Blattner, William A., Kalams, Spyros A., Walker, Bruce D.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113072/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10559335/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.12.10191-10198.1999
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