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Increased levels of glutathione S-transferase pi transcript as a mechanism of resistance to ethacrynic acid.

Subpopulations of HT 29 human colon carcinoma cells (HT/M and HT/S) were selected for resistance to the glutathione S-transferase (GST) inhibitor ethacrynic acid (EA). Both clones displayed a 2-fold resistance to the selection agent and required its constant presence for the maintenance of the resis...

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Detalles Bibliográficos
Main Authors: Kuzmich, S, Vanderveer, L A, Walsh, E S, LaCreta, F P, Tew, K D
Formato: Artigo
Idioma:Inglês
Publicado: 1992
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1130664/
https://ncbi.nlm.nih.gov/pubmed/1731759
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