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Hyperphosphorylation of the Hepatitis C Virus NS5A Protein Requires an Active NS3 Protease, NS4A, NS4B, and NS5A Encoded on the Same Polyprotein

The nonstructural protein NS5A of hepatitis c virus (HCV) has been demonstrated to be a phosphoprotein with an apparent molecular mass of 56 kDa. In the presence of other viral proteins, p56 is converted into a slower-migrating form of NS5A (p58) by additional phosphorylation events. In this report,...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Neddermann, Petra, Clementi, Angelica, De Francesco, Raffaele
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113049/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10559312/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.12.9984-9991.1999
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