The V Protein of Simian Virus 5 Inhibits Interferon Signalling by Targeting STAT1 for Proteasome-Mediated Degradation

To replicate in vivo, viruses must circumvent cellular antiviral defense mechanisms, including those induced by the interferons (IFNs). Here we demonstrate that simian virus 5 (SV5) blocks IFN signalling in human cells by inhibiting the formation of the IFN-stimulated gene factor 3 and gamma-activat...

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Podrobná bibliografie

Vydáno v:	J Virol
Hlavní autoři:	Didcock, L., Young, D. F., Goodbourn, S., Randall, R. E.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1999
Témata:	Virus-Cell Interactions
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113042/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10559305/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.12.9928-9933.1999
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