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Proliferation Response to Interleukin-2 and Jak/Stat Activation of T Cells Immortalized by Human T-Cell Lymphotropic Virus Type 1 Is Independent of Open Reading Frame I Expression

Human T-cell lymphotropic virus type 1 (HTLV-1), a complex retrovirus, encodes a hydrophobic 12-kD protein from pX open reading frame (ORF) I that localizes to cellular endomembranes and contains four minimal SH3 binding motifs (PXXP). We have demonstrated the importance of ORF I expression in the e...

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Udgivet i:J Virol
Principais autores: Collins, Nathaniel D., D’Souza, Celine, Albrecht, Björn, Robek, Michael D., Ratner, Lee, Ding, Wei, Green, Patrick L., Lairmore, Michael D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113003/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10516077/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.11.9642-9649.1999
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