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Human T-Cell Leukemia Virus Type 1 pX-I and pX-II Open Reading Frames Are Dispensable for the Immortalization of Primary Lymphocytes

Human T-cell leukemia virus type 1 (HTLV-1) infects and transforms CD4(+) T-lymphocytes both in vivo and in vitro. Although the Tax protein of HTLV-1 has been strongly implicated as a transforming agent, other virally encoded proteins may also play a role in the transformation process. In addition t...

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Detalhes bibliográficos
Main Authors: Robek, Michael D., Wong, Fen-Hwa, Ratner, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109681/
https://ncbi.nlm.nih.gov/pubmed/9557741
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