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Generation of Adenovirus Vectors Devoid of All Viral Genes by Recombination between Inverted Repeats

Direct or inverse repeated sequences are important functional features of prokaryotic and eukaryotic genomes. Considering the unique mechanism, involving single-stranded genomic intermediates, by which adenovirus (Ad) replicates its genome, we investigated whether repetitive homologous sequences ins...

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Publicado no:J Virol
Principais autores: Steinwaerder, Dirk S., Carlson, Cheryl A., Lieber, André
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Gene Therapy
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112965/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10516039/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.11.9303-9313.1999
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