trans-Complementation Analysis of the Flavivirus Kunjin ns5 Gene Reveals an Essential Role for Translation of Its N-Terminal Half in RNA Replication

Recently we described rescue of defective Kunjin virus (KUN) RNAs with small deletions in the methyltransferase and RNA polymerase motifs of the ns5 gene, using BHK cells stably expressing KUN replicon RNA (repBHK cells) as helper (A. A. Khromykh et al., J. Virol. 72:7270–7279, 1998). We have now ex...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Khromykh, Alexander A., Sedlak, Petra L., Westaway, Edwin G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112959/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10516033/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.11.9247-9255.1999
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